The $145–230 Billion Problem in Research
Irreproducible research costs up to $145–230 billion annually worldwide, with up to 20% attributed to contamination. Here's how we're solving it.
Reproducibility is the cornerstone of scientific progress. Yet a growing body of evidence shows that a staggering proportion of published research cannot be replicated, and contamination is one of the leading causes.
The scale of the problem
Some analyses place contamination as a leading cost factor, accounting for more than 20 percent of losses per experiment, though figures can vary. These range from cross-contamination between wells in a microplate to airborne particles altering cell results.
Why current microplates fall short
Standard open microplate systems leave samples exposed during handling, liquid transfers, and incubation. Even with strict protocols and laminar flow cabinets, the risk is never fully eliminated. Automation helps, but it introduces new contamination vectors through robotic pipettors and carousel-style storage.
The IsoraLabs approach
The IsoraPlate replaces the open architecture with a self-sealing protective membrane that covers each well individually. The membrane allows standard pipette access while blocking biological, physical, and chemical contaminants from entering or spreading between wells.
Crucially, the IsoraPlate is a drop-in replacement. It fits existing liquid-handling equipment and requires no retraining. Researchers get meaningfully better contamination control without changing their workflow.
Looking forward
If you are interested in collaborating or learning more, reach out at contact@isoralabs.com.